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However, SOD-1 does inhibit proliferation and migration of smooth muscle cells induced by oxLDL in vitro (315), and overexpression of both SOD-1 and catalase reduce atherosclerosis in Apoe -/- mice (409)

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Hyperlipidemia, characterized by high levels of lipids (fats) in the blood, is a major risk factor for cardiovascular events such as heart attacks and strokes

Biochem Biophys Acta 1546:2143 [DOI] [PubMed] [Google Scholar] 107.Rebouche CJ (2004) Kinetics, pharmacokinetics, and regulation of l-carnitine and acetyl-l-carnitine metabolism