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In vivo, Gi-DR loaded with GSH-responsive LDCs (camptothecin) achieved approximately 90% tumor inhibition in HeLa models, with tumor-selective accumulation (peak at 4 h) and no detectable off-target toxicity [88]

Subsequently, an acetyltransferase that N -acetylates cysteine S -conjugates (Eq

doi: 10.1371/journal.pone.0004756

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40 The first patient was a 39-year-old man with a BMI of 24.98 kg/m 2 and confirmed genetic testing