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Karin I, Borggraefe I, Catarino CB, Kuhm C, Hoertnagel K, Biskup S, et al

Patients on combination therapy should monitor blood glucose levels regularly and discuss potential dose reductions of insulin or sulfonylureas with their healthcare provider during tirzepatide initiation and dose escalation

These fat-soluble buddies can relax in your fat tissues and liver for a pretty long time - think months