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A randomised controlled trial published in Clinical Infectious Diseases demonstrated that Thymosin Alpha-1 treatment in severe COVID-19 patients reduced 28-day mortality by 30% compared to standard care alone.17 While this was acute disease, not long COVID, it confirms the biological plausibility of the immune mechanism

The Nrf2/Keap1 system is responsive to many challenges, particularly to oxidants and electrophiles

The analysis compared data from eight studies of more than 420 children administered conventional therapy and intravenous vitamin C doses between 100 and 250 mg/kg/bw

D.RoneyN.CrawfordJ.ColesC.McClureP

Despite the benign inactive N -glucuronide being the major metabolite, pexidartinib carries a box warning due to drug-induced liver injury (DILI)
