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Growing evidence has depicted that gut microbiota modification leads to augmented SCFA production, which underlies most of the aforementioned beneficial impacts (32)

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41,169,170 Differential diagnoses include entrapment neuropathies, infectious neuropathies, and inflammatory conditions
doi: 10.1093/jn/121.suppl_11.S166 9 de la RosaJStipanukMH

In germ-free mice, not only are macrophages and dendritic cells unable to produce interleukins such as TNF, IFN, and IL-10, but they also indirectly inhibit T-cell activation and maturation, suggesting that SCFAs are an essential and important component in the development of the host immune system (Jiao et al., 2020)