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Frequently studied in neurobiology contexts related to sleep/circadian research models and stress-axis signaling themes (model-dependent)

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278 Additionally, a casein-derived peptide enhanced the TER value, indicating an increase in GI barrier function, and increased the levels of occludin gene and protein expression in in vitro human intestinal epithelial Caco-2 cells, as well as in ex vivo mouse jejunal and ileal loops

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The effect of DSIP on GABA receptors and glutamate receptors in neurons of the hypothalamus, thalamus, cortex, hippocampus, and cerebellum has been at least partially attributed to motor function recovery in test subjects [15, 16, 17]