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A small cardboard or plastic box that sits on the middle shelf of the refrigerator, holding all vials in darkness and organized in one place

Less common: Tingling or numbness in extremities Lightheadedness shortly after administration Drowsiness, particularly with evening doses Shared Risks Both compounds carry the general cautions associated with GH/IGF-1 axis activation: Glucose metabolism: Elevated GH can transiently increase blood glucose and reduce insulin sensitivity, particularly with extended continuous use

[5] Therefore, the entry of 1,3-BPG into the Rapoport-Luebering cycle incurs an energy cost equivalent to two ATP molecules per 1,3-bisphosphoglycerate molecule diverted from glycolysis

This promotes the secretion of COL-I and OC from MSCs and chondrocytes, causing them to differentiate into osteoblasts and exerting anti-osteoporosis effects [49, 50]
