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Description
The truncation reduces IGFBP binding similar to the LR3 modification, but DES IGF-1 retains a much shorter circulating half-life (typically reported in the 20 to 30 minute range) because the rest of the molecule remains susceptible to standard proteolytic clearance
[Google Scholar] 65.Chai C., Waring P
The differences are FDA approval status (weight loss vs diabetes), pricing, and supply availability
In both cases, it doesnt work and can drive the calcium up to dangerous levels
Important: The specific Klow combination has not been systematically evaluated in clinical studies
