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Effect of human plasma exosomes on U1 monocytic cells We previously reported that ALC-induced CYP2E1 expression in monocytic/macrophage cell lines resulted in increased oxidative stress and cytotoxicity 8

Reversible inactivation by hydrogen peroxide

And an H2A deubiquitinase, tumor suppressor BAP1-mediated SLC7A11 inhibition, does not require Nrf2 and ATF4 transcription factors but represses SLC7A11 expression by reducing H2A ubiquitination (H2Aub) on the SLC7A11 promoter (Zhang et al., 2019)

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