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Clinical trial results for CagriSema showed significant improvements in A1C, weight loss, and time in range, marking it as a promising new type 2 diabetes and weight management treatment

doi: 10.3389/fragi.2026.1790247 Received 17 January 2026 Revised 27 February 2026 Accepted 20 March 2026 Published 07 April 2026 Volume 7 - 2026 Edited by Filipe Cabreiro, University of Cologne, Germany Reviewed by Wanzi Yao, Peking University, China Updates Copyright 2026 Mavrych, Shypilova and Bolgova

This effect was significantly blunted in 3-KO mice

[DOI] [PMC free article] [PubMed] [Google Scholar] 26.Finney-Brown T

Potential benefits Based on available literature, clinical trials, and anecdotal/clinical practice reports, these are the benefits most often cited: Fat loss / body composition improvement Reduction in overall body fat, especially subcutaneous & visceral fat