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Seiwerth S, Sikiric P, Rucman R, et al
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The peptide upregulates growth hormone receptors on tendon fibroblasts, enhances neurotrophic factor expression, and promotes angiogenesis through the VEGFR2-Akt-eNOS signaling pathway

Patients considering combination approaches should understand that this represents an unproven strategy that increases cost and injection burden without documented benefit

10.1073/pnas.96.22.12905 142
