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doi:10.1016/j.ajpath.2016.09.004

These microbial-derived molecules act as pathogen-associated molecular patterns (PAMPs), activating pattern recognition receptors (PRRs) on peripheral immune cells and brain-resident microglia

Roth E, Oehler R, Manhart N, et al

This includes providing restoration of IS by incorporating protection, detection, and reaction capabilities

Cell clustering was performed using the Louvain method with a resolution of 0.3
