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PMC8355064 Cationic amphiphilic drugs activate MRGPRX2 pharmacophore modeling and human wheal-and-flare

Appears to modulate gene expression related to vascularization and nitric oxide signaling, suggesting potential benefits for blood flow and antioxidant activity8

Clin Pharmacol Ther 1991;50:695-701

Balmer FM, Smith FA, Leach LJ, et al

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