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Description
Accumulation of OTA in the kidney was higher than AFs, possibly due to their rapid metabolism (Corcuera et al., 2015), and its accumulation correlates with kidney injury

The third factor is electrolyte depletion
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Although the drugs can effectively reduce weight and improve some metabolic indicators, they are often accompanied by a decrease in fat-free mass, and this contradiction mainly arises from the inherent differences in research models, physiological backgrounds, and intervention conditions