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Currently, probiotic organisms are used to improve adaptive and innate immunity in fish (Tran et al., 2022)

In the ovalbumin (OVA)-induced allergic conjunctivitis C57BL/6 mice model, quercetin was able to reduce IgE, Histamine, IL-4, and TNF-, substance P in a concentration-dependent manner in the AC mouse model, and the effect was similar to mice treated with olopatadine [10]