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Description
Dyes Pigments 174 , 108024 (2020)

Compounds that chelate free metal ions in a way that prevents them from generating free radicals offer promise in the treatment of neurodegenerative diseases and other chronic diseases in which metal-induced oxidative damage may play a pathogenic role (21)

that is, TRPV1-mediated pain perception can be inhibited by extracellular zinc entry into cells via transient receptor potential A1 (TRPA1) channels or zinc transporters [106]

A genetic study found that the interstitial deletion of chromosome 4q in a child with autism contributed to hemizygosity of the glutamate receptor AMPA2, glycine receptors GLRB and GLRA3, and neuropeptide receptors NPY1R and NPY5R [75]

These manifestations of synovial lesions are mediated by various cell types in the synovial lining of the joint cavity (Scanzello and Goldring, 2012)
