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However, it has been revealed that high doses of carnitine can improve the clinical manifestations of these disorders [55, 56]

The purpose of this review is to comprehensively summarize the multidimensional biological effects of the carnitine pool beyond its traditional role in fatty acid oxidation and to summarize the systemic effects mediated by carnitine/acylcarnitine to provide new perspectives for pharmacological research and treatment innovation and new strategies for the prevention and treatment of a variety of diseases

Propionyl-L-carnitine increases Apoptosis , Bax , and reduces NF-B , VCAM-1 , MCP-1 , and survivin

5-HT acts as a vasoconstrictor at the endpoint and is the factor that facilitates migraine attacks (190, 191)

( 10.1095/biolreprod.112.102020) [DOI] [PubMed] [Google Scholar] Aliabadi E, Soleimani Mehranjani M, Borzoei Z, Talaei-Khozani T, Mirkhani H, Tabesh H.2012