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The O2 is a highly unstable, highly reactive, and short-lived form of ROS and reacts quickly to become membrane-impermeable

GHK-Cu GHK-Cu Research Grade Peptide Overview Overview GHK-Cu (glycyl-L-histidyl-L-lysine copper (II) complex) is a research-grade copper-peptide supplied for in vitro investigation of cell signaling, extracellular matrix regulation, and cellular migration

If it suffers one-electron reduction, there is formation of a very unstable semiquinone radical, which reacts rapidly with molecular oxygen resulting in regeneration of the parent compound and production of a superoxide anion that yields H 2 O 2 via enzymatic or spontaneous dismutation

J Neuropathol Exp Neurol 49:591599

Deacon, C