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In case of sperms, studies have shown that NAC helps to maintain sperm DNA integrity by improved replacement of histones with protamine [23, 24]
This quick clearance limits the delivery of therapeutic payload over the long period of time for which the mucoadhesion is designed, reducing the bioavailability of inhaled therapeutics 145

Journal of Asthma 2005;42(10):85964

Jiang 10 et al
Reactive oxygen species, oxidative damage, and antioxidant defence mechanism in plants under stressful conditions
