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Description
The COA reports particle counts at each threshold against the specification limit

Patients with pancreatic insufficiency may have reduced cobalamin absorption (because pancreatic enzymes normally assist with the displacement of salivary haptocorrin binding protein by intrinsic factor), although such patients rarely become cobalamin deficient
Avoid freezing acidified solutions
Hydroxocobalamin can cause harmless red discolouration of urine, which patients should be forewarned about to prevent alarm

This 48-week, randomized, double-blind, placebo-controlled study enrolled 338 adults with obesity or overweight with at least one weight-related comorbidity
