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& Yanker, B.A

found that PBT434, a novel compound with moderate iron affinity, can protect the survival of SNpc neurons, improve nigrostriatal connectivity and motor function in mice, without disrupting normal iron homeostasis (229)
Endothelial cell dysfunction results in ECM metabolism disorders, VSMC apoptosis, aortic wall thinning, and then aortic aneurysms and dissection

To visualize similarities and differences between the samples, S-plots of data pairs of accurate mass and retention time of each metabolite were calculated based on orthogonal partial least squares discriminant analysis (OPLS-DA)

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