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462 In cell and animal research, magnesium L-threonate, a magnesium salt that more readily permeates the central nervous system, has been found to raise brain magnesium levels, improve brain structure and function, prevent nerve damage due to toxicity or low oxygen levels, and reduce symptoms of neurological diseases

PMID 19707742

In the same mouse model, a decreased glycolytic capacity was demonstrated in the optic nerve (36)

Kuo HC: Repeated intravesical onabotulinumtoxina injections are effective in treatment of refractory interstitial cystitis/bladder pain syndrome

In response to UCB stimulation, IL-1beta, TNF-alpha, NF-B, and MAPK pathways have been shown to serve significant functions in cytotoxicity and cytokine production, which led to UCB-induced neurotoxicity [31]