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Description
The analysis of an unsolved loop region near the proposed spermidine binding site revealed a new pocket that was demonstrated to bind glutathionylspermidine in an inverted orientation
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Nourishes skin with antioxidants
For in vitro experiments, embryonic rat cardiomyocytes (H9c2 cells) exposed to hypoxia-reoxygenation (HR) showed a time-dependent increase in gp91phox (a marker for ROS production by NADPH oxidases), caspase-3 (a key mediator of apoptosis) expression, and a decrease in the glutathione redox ratio
In cosmetic science, this translates to an active that can intervene in both oxidative stress pathways and melanogenesis regulation, making it one of the few ingredients that offers dual antioxidant and brightening performance
