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Mechanism: Promotes angiogenesis, fibroblast migration, and collagen synthesis

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When supplemented in combination with methimazole, berberine significantly altered the microbiota composition of patients, decreasing the abundance of the pathogenic bacteria Chryseobacterium indologenes and Enterobacter hormaechei while simultaneously increasing the content of the beneficial bacteria Lactococcus lactis ( 185 )

OCR was measured following sequential injections of 2.5 M oligomycin A, 2.5 M BAM15, and 0.5 M rotenone/antimycin A (all Agilent, Seahorse XF T Cell Metabolic Profiling Kit, 103772-100) according to the manufacturers instructions