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Using cannabinoid compounds with no affinity for CB1 receptors from CNS (central nervous system), which drastically limits the selection of effective solutions, or formulating them so that they cannot cross the BBB are two practical ways to avoid the psychotropic action of cannabinoid compounds

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Moreover, in a randomized, double-blind, placebo-controlled, phase 2 trial to validate the safety and efficacy of ebselen for the prevention of noise-induced hearing loss [84], 83 participants were allocated to receive 200, 400, or 600 mg ebselen or placebo before a calibrated sound challenge (4 h of pre-recorded music delivered by insert earphones)

The Research: What Studies Actually Show Tissue Repair Mechanisms in Animal Models A 2026 peer-reviewed review published in the International Journal of Molecular Sciences examined the mechanistic basis for BPC-157''s reported tissue repair effects