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Description
In both current studies, the safety data with cagrilintide were consistent with data from previous studies with no new safety or tolerability issues observed [4, 7, 10]

References Cauley, J

The unique pharmacological profile of tirzepatide allows a greater engagement of the GIP receptor, mimicking the actions of native GIP, compared to the GLP-1 receptor, where it activates biased downstream signals favoring cAMP generation over beta-arrestin recruitment, resulting in reduced receptor internalization and degradation 2
Small 12 (10), 13691377 (2016)

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