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Description
doi: 10.1111/j.1749-6632.1996.tb21132.x
doi: 10.1097/SCS.0000000000008865
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Sickle cell disease is a common hereditary hemoglobinopathy caused by a point mutation in -globin that promotes the polymerization of deoxygenated hemoglobin, leading to red cell distortion, hemolytic anemia, microvascular obstruction, and ischemic tissue damage
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