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Valproic acid (VPA) is a broad-spectrum antiepileptic drug and is usually well tolerated, but rare serious complications may occur in some patients receiving VPA chronically, including haemorrhagic pancreatitis, bone marrow suppression, VPA-induced ...
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Targeting mitochondria as a therapeutic approach to inhibit or slow down PD formation and progression seems to be an exciting issue

They are difficult for the liver to process