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For example, studies performed in murine J774A.1 macrophages showed that TMAO induced stress and led to increased protein expression of GRP94 and HSP70, which may participate in the abnormal activation of macrophages involved in foam cell formation (Mohammadi et al., 2018)
Further, each step is carried out by different members of the gut microbial community
IDPM: PMC3784205
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Takhshid MA, et al
