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Studies have shown that inhibiting PHGDH expression or activity can significantly suppress metabolic reprogramming in tumor cells, demonstrating potential anti-tumor effects

Macrophage polarization and classification are critical for their diverse roles in immune function

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Additional documented functions include the biosynthesis of vitamins, the metabolism and deconjugation of bile salts, diverse enzymatic activities that contribute to nutrient bioavailability, and the neutralization of dietary or microbial toxins ( Probiotics also support intestinal electrolyte absorption, influence lipid metabolism, and can bind directly to Gram-negative pathogens

Uptake and metabolization of serotonin by granulosa cells form a functional barrier in the mouse ovary