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In the case of skin injury, AMPs expression is highly up-regulated at the wound edge due to increased synthesis by keratinocytes and deposition from degranulation of recruited neutrophils, which indicates that AMPs are potential wound-healing stimulator

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For thymosin beta-4, the intracellular role in actin regulation is fundamental cell biology, and its extracellular repair signaling has been tied to angiogenesis, cell migration, anti-inflammatory activity, and even cardiac tissue effects that motivated the injectable myocardial-infarction program

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