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2.2 Identification and enrichment strategies A variety of chemical tools have been developed to investigate lysine lactylation at the proteomics level

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Furthermore, it promotes the ROS-dependent E2F1-mediated degradation of HIF-1, which decreases VEGF expression [23]

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This refers to the fact that the RDA is only 75-90 mg/day for adults and Pauling recommended taking 1-2 grams of vitamin C daily8

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The downregulation of the cystine/glutamate transporter (system Xc - ) constitutes the initial ferroptotic signal

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Salih DAM, Brunet A: FoxO transcription factors in the maintenance of cellular homeostasis during aging

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