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IL-18 is expressed in the intercalated cell of human kidney

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Sedimentation coefficient distributions were corrected to standard conditions (water at 20 C, s20,W)

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They can bind G-protein-coupled estrogen receptor 1 (GPR30), with effects driven by both genomic and non-genomic regulation involving different cellular signalling pathways, such as intracellular increase of calcium or NO levels (Reference Ropero, Alonso-Magdalena and Ripoll75) , as observed in human endothelial cells after stimulation with equol 100 nM (Reference Rowlands, Chapple and Siow76)

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