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The study, conducted on 976 participants, showed that vitamin B12 levels were significantly lower in people who were obese and overweight (9)

Some potential skin-related effects under exploration include: Accelerated healing from minor irritations or surface damage Reduced redness and sensitivity through inflammation support Improved hydration by restoring barrier lipids and integrity Structural support for skin undergoing stress or environmental exposure These benefits may be especially helpful for those with sensitive, reactive, or dry skin looking to restore balance without triggering flare-ups

For example, vitamin D induces BDNF release via calcium signaling by upregulating voltage-gated calcium channels, while folate and B vitamins are involved in neuroprotective effects through limiting neurotoxic homocysteine levels, which inhibits neurotrophic signaling [221]

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doi: 10.1016/j.pnpbp.2012.11.008 10 ShiJLevinsonDFDuanJSandersARZhengYPeerIet al