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USP13 interacts with cellular IAP2 (cIAP2), stabilizing cIAP2 proteins in colorectal cancer (CRC) cells

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The inherent multi-component, multi-target nature of TCM formulations and natural compounds further complicates this challenge

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Volles MJ, Lansbury Jr PT

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Thorough cooking ensures a thermally induced conformational change of lentinan and leads to its inactivation

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