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Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1

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This mechanism is particularly relevant when considering its potential for scar lightening

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SUMO fusion technology for difficult-to-express proteins

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Chronic inflammation often leads to pain and discomfort, making recovery difficult

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In this cascade, the activation of caspase-1 within the inflammasome complex leads to the cleavage of gasdermin-D (GSDMD) and the precursors of interleukin-1 (IL-1) and interleukin-18 (IL-18), marking the cell for pyroptotic death (Martinon et al., 2002

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