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[25] Both vitamin B 12 and folate are involved in the one-carbon metabolism cycle

So that's that's the theory

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Metabolic Studies : Explored for its role in glucose and fatty acid uptake, fat metabolism modulation, and potential counteraction of glucocorticoid-induced side effects like muscle wasting in experimental anti-inflammatory therapies

Higher NAD is associated with SIRT1 activity, studied in relation to cellular repair, stress response, and aging pathways