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Two patients with type1 diabetes with hypoleptinemia associated with acquired lipodystrophy were administered r-metHuLeptin

With the treatment time as the horizontal coordinate, the tumor volume and the mouse body weight as the vertical coordinate, the tumor growth curve and the mouse body weight change curve were plotted respectively

[PubMed] de la Villa P, Kurahashi T, Kaneko A

Rachelefsky, G