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Potential applications of NRF2 modulators in cancer therapy
10.1002/iub.2020 [DOI] [PubMed] [Google Scholar] Springett G
Glutathione peroxidase 4 (GPX4) is a selenoenzyme that uses GSH as a co-factor to regulate lipid peroxidation of cell membranes during increased oxidative stress
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Oxidation at SOX2s Cys265 site disrupted its activity, sensitizing cells to lipid peroxidation and ferroptosis (Wang et al
