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In contrast, M2 polarization, associated with tumor promotion, is activated by signals like IL-4, IL-10, and TGF-, primarily through the JAK/STAT6, PI3K/AKT/mTOR, and TGF-/SMAD pathways, promoting tissue repair, immune suppression, and angiogenesis

Aydin R, Bekci T, Bilgici MC, Polat AV
Targeting Multiple Neurodegenerative Diseases Etiologies with Multimodal-Acting Green Tea Catechins
