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In fact, its a commonly prescribed medication for morning sickness

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Cardiovascular and Musculoskeletal Research Applications

Q: Could you talk about vitamin B supplementation

Substitution of these critical leucine residues to tryptophan eliminated binding affinity, highlighting the importance of maintaining key hydrophobic contacts of leucine side chains, and not general hydrophobicity, which is further exemplified by the evolutionary conservation of leucine residues in LD motifs 41