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NMDAR-mediated intracellular Ca 2+ signals can increase the BBB permeability by inducing NO release [24,108,128] and myosin light chain (MLC) phosphorylation through the Ca 2+ -dependent recruitment of Rho-kinase (ROCK) and MLC kinase (MLCK) [108]

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Immunostaining of organoids Immunohistochemical detection of cytokeratin 18 (CK18) and cytokeratin 19 (CK19) was performed by an indirect two-step method in paraffin-embedded sections

Although, the PET-depolymerization performance declines with increasing PET crystallinity, DmPETase and LCC ICCG still manage to degrade semi-crystalline PET, releasing 30.3 g/mg PET and 35.0 g/mg PET of hydrolysis products, respectively

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