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Description
Spontaneous apoptosis of dendritic cells is efficiently inhibited by TRAP (CD40-ligand) and TNF-alpha, but strongly enhanced by interleukin-10
Options Gastroenterol
Administration of paclitaxel alone led to tumor reduction followed by tumor expansion, whereas CB-839 alone or in combination with paclitaxel reduced tumor growth with no tumor regrowth over time [42]
However, translating these discoveries into clinically viable therapies requires further preclinical and clinical validation
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