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Oxidative stress also activates the Kelch-like ECH-associated protein 1 (Keap1)-Nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE) redox regulator pathway, releasing Nrf2 to regulate the expression of genes that control antioxidant, inflammatory and immune system responses, facilitating GSH activity

Sinyukhin, A

Thus, a DAMP can increase the detrimental effects of virus-derived PAMPs, for which reason it seems likely that the positive association of diverse DAMPs with COVID-19 severity reflects a causal role, rather than being merely correlative

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The Mla pathway in Acinetobacter baumannii has no demonstrable role in anterograde lipid transport
