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Though these unsaturated FAs are susceptible to peroxidation, they can nonetheless reduce free radicals, oxidative stress, and ferroptosis

Conclusion In this study, a LAB strain demonstrated good in vitro antioxidative effect was screened out through a series of experimental evaluation

For example, esculetin (20-60 mg/kg) can inhibit the production of inflammatory factors such as IL-1, IL-6, TNF-, C-C motif chemokine ligand 2 and iNOS in Escherichia coli-induced sepsis mice by inhibiting the NF-B and STAT1/STAT3 signaling pathways (95)

Taken together, APS functions as an anti-inflammatory agent in animals and exerts its anti-inflammation mainly by inhibiting NF-B signaling pathways and reducing expression of pro-inflammatory cytokines

It must be combined with other solutions, such as semaglutide injection, physical activity, a balanced diet, and others