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Relationship between CGRP and energy metabolism of migraine As a multifunctional neuropeptide, CGRP plays an important role in the pathophysiology of migraine by regulating neurogenic inflammation and nociceptive signal input (Russell et al., 2014

"Express Scripts should explain why it has chosen not to set `maximum allowable pricing' across the board, rather than attempting to shift responsibility to pharmacists and shift costs to its customers," the group said

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The end result of this cascade is the production of cross-linked fibrin clots

Metabotropic glutamate receptors (mGLuRs) are distributed throughout the CNS, and carry out multiple functions in maintaining synaptic transmission