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Description
Briefly, samples were spiked with 10 L of both Avantis SPLASH Lipidomix and an in-house hydrophilic spike mix (L-acetylcarnitine-d 3 :HCl, 13 C 5 -adenosine (ribose), adenosine triphosphate-d 4 (ammonium salt, ribose), L-alanine-d 3 , L-aspartic acid-d 3 , carnitine-d 3 :HCl, creatinine-d 3 , U- 13 C 6 -D-glucose, U- 13 C 6 -D-glucose-6-phosphate (disodium salt, hydrate), L-lysine-d 4 :HCl, methyl-d 3 -malonic acid, 13 C 6 -niacinamide, succinic acid-d 6 and L-valine-d 8 at 10 g/mL and L-lactate-d 3 (sodium salt) at 2 g/mL, in 50:50 methanol:water)

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