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28 In accordance with the reported rates of metastasis in the literature, ranging from 26% to 44%, metastasis occurred in 27% of patients included in our review, with a median time to metastasis of 27 months

Al-Majed and colleagues [140] found that carnitine deficiency and oxidative stress are risk factors during development of cisplatin (CDDP)-induced cardiomyopathy and that carnitine supplementation, using propionyl-l-carnitine, prevents the progression of CDDP-induced cardiotoxicity

doi: 10.1136/openhrt-2018-000890 36 DongZ.LiangZ.GuoM.HuS.ShenZ.HaiX

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