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Nrf2 coordinately activates these genes and exerts a protective function against xenobiotic and oxidative stresses ( Figure 1

LRRK2 is an enzyme with both kinase and GTPase activities (Steger et al., 2016), which are important for exocytosis of synaptic vesicles, and endolysosomal and Golgi apparatus protein sorting (West et al., 2005

doi: 10.1016/j.biomaterials.2012.08.007 429 PengYZhuXQiuL