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K.CulmseeC.et al (2008)
Handbook of Lung Targeted Drug Delivery Systems

53.3 Pathways of paracetamol metabolism

Conditional knockout of the Ccl2 gene in LECs exacerbates cardiac dysfunction, impedes lymphangiogenesis, and impairs macrophage clearance via cardiac afferent lymphatic vessels, underscoring the critical role of LEC-expressed CCL2 in coordinating lymphatic expansion and immune cell trafficking (189)